It's crucial to hold onto jokers until you can utilize them wisely because they can be used as wild cards to finish sets & runs. Players may position themselves for success isbte. inn Rummy 7-Up by creating a strong opening strategy that emphasizes creating sets, observing opponents' discards, and making efficient use of jokers. In order to increase your chances of winning the game of Rummy 7-Up, jokers are a crucial component. Jokers are wild cards that can be used in sets and runs of Rummy 7-Up to replace any other card.