Knowing when to save jokers and wild cards for later use and when to use them right away is a crucial part of using them effectively. When a joker or wild card can be used to finish a higrummy applicationsh-value combination, it can sometimes be advantageous to hold onto it. It might be more beneficial in the short run to use it right away to create a lower-value combination in other situations. You can maximize the effect of jokers and wild cards on your overall strategy by carefully weighing these options and making well-informed decisions. Things to Take Into Account.