If the game goes poorly, holding onto a card for too long can result in needless point accumulation, while dropping it too early may allow your opponents to use it to finish their melds. As a general rule, yoyono new gameu should evaluate the card's value in light of your current hand. It might be prudent to discard a card sooner rather than later if you have no immediate use for it and it does not fit into any possible melds. Take into account the cards that have already been discarded as well. If you observe that opponents are regularly picking up particular cards, it can mean that they are attempting to make a particular meld.