Prioritizing the removal of valuable cards that are unlikely to be helpful in creating sets & runs is one important tactic. For instance, it could be a good idea for a plvegas rush slotsayer to discard several high-value cards of different suits if they don't belong in a set or run. This will make room in their hand for more valuable cards. In addition, players should be aware of the cards that their opponents have discarded. Based on this information, they can decide which cards are safe to discard & which ones to keep.